Affiliation:
1. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231
Abstract
ABSTRACT
The seven
Mycobacterium tuberculosis whiB
-like genes encode small proteins postulated to be transcriptional regulators. A systematic real-time reverse transcription-PCR analysis following exposure to antibiotics and a variety of growth and in vitro stress conditions indicates differential, and in some cases dramatic, transcription modulations for the different
M. tuberculosis whiB
family members. This information together with biochemical analyses of the
whiB1
to
whiB7
gene products will be important for understanding the biology of this novel family of proteins in mycobacteria and related actinomycetes.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
167 articles.
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