Can We Use Imipenem and Meropenem Vitek 2 MICs for Detection of Suspected KPC and Other-Carbapenemase Producers among Species of Enterobacteriaceae?-Reference-Cited by-同舟云学术

Can We Use Imipenem and Meropenem Vitek 2 MICs for Detection of Suspected KPC and Other-Carbapenemase Producers among Species of Enterobacteriaceae?

Published:2011-02 Issue:2 Volume:49 Page:697-701
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Pasteran Fernando¹,Lucero Celeste¹,Soloaga Rolando²,Rapoport Melina¹,Corso Alejandra¹

Affiliation:

1. Servicio Antimicrobianos, Departamento Bacteriología, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS Carlos G. Malbrán, Ministerio de Salud y Ambiente de la Nación, Ciudad Autónoma de Buenos Aires, Argentina

2. Servicio de Microbiología, Hospital Naval Buenos Aires Cirujano Mayor Pedro Mallo, Ciudad Autónoma de Buenos Aires, Argentina

Abstract

ABSTRACT Imipenem and meropenem Vitek 2 MICs were evaluated for a panel of 104 Enterobacteriaceae for identification of carbapenemase producers. The sensitivity and specificity values for the new CLSI interpretative criteria (CLSI document M100-S20-U, 2010) were 98% and 83% for imipenem and 76% and 83% for meropenem, respectively. We propose an algorithm that is highly sensitive (98%) and specific (94%) for carbapenemase screening based on the combined use of imipenem and meropenem MICs.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01178-10

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