Butirosin, a New Aminoglycosidic Antibiotic Complex: Isolation and Characterization-Reference-Cited by-同舟云学术

Butirosin, a New Aminoglycosidic Antibiotic Complex: Isolation and Characterization

Published:1972-08 Issue:2 Volume:2 Page:84-88
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Dion Henry W.¹,Woo Peter W. K.¹,Willmer Neil E.¹,Kern Donald L.¹,Onaga John¹,Fusari Salvatore A.¹

Affiliation:

1. Biological Research and Development Department, Research and Development Division, Parke, Davis & Company, Detroit, Michigan 48232

Abstract

Butirosin, a new water-soluble aminoglycosidic antibiotic complex, active against gram-positive and gram-negative bacteria, has been isolated from fermentation filtrates of Bacillus circulans by ion exchange. The complex has been resolved into isomeric A and B components, C 21 H 41 N 5 O 12 , by means of Dowex 1 × 1 or Dowex 1 × 2 chromatography. Properties of the free bases and the N, N′, N″, N‴ -tetraacetyl derivatives of butirosin A and B are given.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.2.2.84

Reference8 articles.

1. Colorimetric determination of boron using carmine;Hatcher J. T.;Anal. Chem.,1950

2. Butirosin, a new aminoglycosidic antibiotic complex: antibacterial activity in vitro and in mice;Heifetz C. L.;Antimicrob. Ag. Chemother.,1972

3. Butirosin, a new aminoglycosidic antibiotic complex: bacterial origin and some microbiological studies;Howells J. D.;Antimicrob. Ag. Chemother.,1972

4. Quantitative determination of the components of neomycin by paper chromatography;Majumdar M. K.;Aaal. Chem.,1967

5. Separation of acetylated neomycin B and C by paper chromatography;Pan S. C.;Anal. Chem.,1956

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