Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes-Reference-Cited by-同舟云学术

Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes

Published:1993-02 Issue:2 Volume:61 Page:781-784
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Shaffer J M¹,Baker-Zander S A¹,Lukehart S A¹

Affiliation:

1. Department of Medicine, University of Washington, Seattle 98195.

Abstract

Rabbit antisera to Leptospira interrogans, Borrelia hermsii, and Treponema phagedenis biotype Reiter, reactive to shared spirochetal antigens, failed to enhance phagocytosis of Treponema pallidum by macrophages, while immunoglobulin G to Treponema pallidum subsp. pertenue and Treponema paraluiscuniculi promoted phagocytosis. Opsonic antibodies are directed to pathogen-restricted, not shared spirochetal, antigens.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.61.2.781-784.1993

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