Affiliation:
1. Program in Biochemical Sciences, Department of Biology, Princeton University, Princeton, New Jersey 08540
2. Department of Biological Sciences, Stanford University, Stanford, California 94305
Abstract
An
Escherichia coli
mutator gene,
mutT
, has been shown by P1-mediated crosses to map between the leucine and azide loci. The
mutT1
and
azi-r
alleles cotransduce with a frequency of >92%. In
mutT1/mutT
+
merodiploids, the
mutT1
phenotype is recessive; in
mutT1
/F′
trp
or
mutT1
/F′
lac
merodiploids, the
mutT1
allele has a
trans
effect. The gene can mutate λ and T7 phage but not T1, T3, T4, T5, and S13.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
64 articles.
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