In vitro activities of lomefloxacin, tetracycline, penicillin, spectinomycin, and ceftriaxone against Neisseria gonorrhoeae and Chlamydia trachomatis

Author:

Talbot H1,Romanowski B1

Affiliation:

1. Clinical Investigation Unit, Sexually Transmitted Disease Control, Alberta Health, Edmonton, Canada.

Abstract

In vitro lomefloxacin was highly active against 208 penicillin-susceptible and -resistant isolates of Neisseria gonorrhoeae. However, its MIC and MBC against 10 isolates of Chlamydia trachomatis were 2 and greater than 4 micrograms/ml, respectively.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference15 articles.

1. Barry A. L. 1976. Agar dilution techniques p. 76-90. In A. L. Barry (ed.) The antimicrobic susceptibility test: principles and practices Lea & Febiger Philadelphia.

2. In vitro activity of clavulanic acid, amoxicillin, and ticarcillin against Chlamydia trachomatis;Bowie W. R.;Antimicrob. Agents Chemother.,1986

3. Prediction of efficacy of antimicrobial agents in treatment of infection due to Chlamydia trachomatis;Bowie W. R.;J. Infect. Dis.,1978

4. Dillon J. R. 1983. Laboratory methods for Neisseria gonorrhoeae (MIC auxotype screening for PPNG). Department of Health and Welfare Ottawa Canada.

5. In vitro activity of a group of broad-spectrum cephalosporins and other ,-lactam antibiotics against Chlamydia trachomatis;Hammerschlag M. R.;Antimicrob. Agents Chemother.,1983

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