A New Shiga Toxin 2 Variant (Stx2f) from Escherichia coli Isolated from Pigeons

Author:

Schmidt Herbert1,Scheef Jürgen1,Morabito Stefano2,Caprioli Alfredo2,Wieler Lothar H.3,Karch Helge1

Affiliation:

1. Institut für Hygiene und Mikrobiologie der Universität Würzburg, 97080 Würzburg,1 and

2. Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy2

3. Institut für Mikrobiologie und Tierseuchen der Freien Universität Berlin, 10115 Berlin,3 Germany, and

Abstract

ABSTRACT We have isolated Shiga toxin (Stx)-producing Escherichia coli (STEC) strains from the feces of feral pigeons which contained a new Stx2 variant gene designated stx 2f . This gene is most similar to sltIIva of patient E. coli O128:B12 isolate H.I.8. Stx2f reacted only weakly with commercial immunoassays. The prevalence of STEC organisms carrying the stx 2f gene in pigeon droppings was 12.5%. The occurrence of a new Stx2 variant in STEC from pigeons enlarges the pool of Stx2 variants and raises the question whether horizontal gene transfer to E. coli pathogenic to humans may occur.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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