The Lactate-Proton Symport of Saccharomyces cerevisiae Is Encoded by JEN1-Reference-Cited by-同舟云学术

The Lactate-Proton Symport of Saccharomyces cerevisiae Is Encoded by JEN1

Published:1999-04-15 Issue:8 Volume:181 Page:2620-2623
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Casal Margarida¹,Paiva Sandra¹,Andrade Raquel P.¹,Gancedo Carlos²,Leão Cecília¹

Affiliation:

1. Centro de Ciências do Ambiente, Departamento de Biologia, Universidade do Minho, 4719 Braga Codex, Portugal,1 and

2. Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-UAM, 28029 Madrid, Spain2

Abstract

ABSTRACT A mutant of Saccharomyces cerevisiae deficient in the lactate-proton symport was isolated. Transformation of the mutant with a yeast genomic library allowed the isolation of the gene JEN1 that restored lactate transport. Disruption of JEN1 abolished uptake of lactate. The results indicate that, under the experimental conditions tested, no other monocarboxylate permease is able to efficiently transport lactate in S. cerevisiae .

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.181.8.2620-2623.1999

Reference22 articles.

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