Affiliation:
1. Section des Maladies Infectieuses, Service de Médecine et Laboratoire d'Investigation Clinique, Institut Jules Bordet, 1000 Brussels, Belgium
Abstract
The bactericidal activity of clindamycin, chloramphenicol, and gentamicin alone and of gentamicin plus clindamycin and gentamicin plus chloramphenicol was studied on 8 strains of
Escherichia coli
and 10 strains of
Bacteroides fragilis
isolated from clinical material. Gentamicin did not interfere with the activity of clindamycin or chloramphenicol against
B. fragilis
. The activity of gentamicin against
E. coli
was not influenced by clindamycin, but chloramphenicol suppressed the rapid bactericidal activity of gentamicin in seven out of eight strains of
E. coli
examined.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
19 articles.
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