Affiliation:
1. Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts
Abstract
ABSTRACT
The activity of a fourth conserved tyrosine site-specific recombinase (Tsr) of
Bacteroides fragilis
was characterized. Its gene,
tsr19
, is adjacent to
mpi
, encoding the global DNA invertase regulating capsular polysaccharide biosynthesis. Unlike the other described Tsrs of
B. fragilis
, Tsr19 brings about inversion of two DNA regions, one local and one located distantly.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology