Phosphoproteome Dynamics of Streptomyces rimosus during Submerged Growth and Antibiotic Production

Author:

Šarić Ela1,Quinn Gerry A.12ORCID,Nalpas Nicolas3,Paradžik Tina1,Kazazić Saša1,Filić Želimira1,Šemanjski Maja3,Herron Paul4ORCID,Hunter Iain4,Maček Boris3,Vujaklija Dušica1ORCID

Affiliation:

1. Division of Physical Chemistry, Institute Ruđer Bošković, Zagreb, Croatia

2. Centre for Molecular Biosciences, Ulster University, Coleraine, United Kingdom

3. Proteome Center Tübingen, University of Tübingen, Tübingen, Germany

4. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

Abstract

Streptomyces rimosus is best known as a primary source of oxytetracycline (OTC). The significant global market value of OTC highlights the need for a better understanding of the regulatory mechanisms that lead to production of this antibiotic.

Funder

Unity through Knowledge Fund

Deutsche Forschungsgemeinschaft

EC | Horizon Europe | Excellent Science | HORIZON EUROPE Marie Sklodowska-Curie Actions

EC | European Regional Development Fund

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

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