Comprehensive Analysis Reveals the Evolution and Pathogenicity of Aeromonas , Viewed from Both Single Isolated Species and Microbial Communities-Reference-Cited by-同舟云学术

Comprehensive Analysis Reveals the Evolution and Pathogenicity of Aeromonas , Viewed from Both Single Isolated Species and Microbial Communities

Published:2019-10-29 Issue:5 Volume:4 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Zhong Chaofang¹²,Han Maozhen¹^ORCID,Yang Pengshuo¹,Chen Chaoyun¹,Yu Hui³,Wang Lusheng²,Ning Kang¹

Affiliation:

1. Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Key Laboratory of Bioinformatics and Molecular Imaging, Department of Bioinformatics and Systems Biology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China

2. Department of Computer Science, City University of Hong Kong, Kowloon, Hong Kong, China

3. Clinical Laboratory, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

Abstract

Aeromonas has long been known as a gastrointestinal pathogen, yet it has many species whose evolutionary dynamics and genetic diversity had been unclear until now. We have conducted pan-genome analysis for 29 Aeromonas species and revealed a high level of genome plasticity exhibited by hundreds of gene expansions and contractions, horizontally transferred genes, and mobile genetic elements. These species also contained many virulence factors both identified from single isolated species and microbial community. This pan-genome study could elevate the level for detection and prevention of Aeromonas infections.

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modelling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.00252-19

Reference86 articles.

1. Aeromonas spp. clinical microbiology and disease

2. Aeromonas-Associated Infections in Developing Countries

3. The Genus Aeromonas : Taxonomy, Pathogenicity, and Infection

4. Aeromonas spp. human infection: retrospective study in the region of Sousse, 2011 - 2015;Bargui H;Tunis Med,2017

5. Detection of putative virulence genes in Aeromonas isolates from humans and animals

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