Comparative Genomics of Mycobacterium avium Complex Reveals Signatures of Environment-Specific Adaptation and Community Acquisition-Reference-Cited by-同舟云学术

Comparative Genomics of Mycobacterium avium Complex Reveals Signatures of Environment-Specific Adaptation and Community Acquisition

Published:2021-10-26 Issue:5 Volume:6 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Keen Eric C.¹²^ORCID,Choi JooHee¹^ORCID,Wallace Meghan A.²,Azar Michelle³^ORCID,Mejia-Chew Carlos R.⁴^ORCID,Mehta Shail B.⁴^ORCID,Bailey Thomas C.⁴^ORCID,Caverly Lindsay J.³^ORCID,Burnham Carey-Ann D.²⁴⁵⁶^ORCID,Dantas Gautam¹²⁶⁷^ORCID

Affiliation:

1. The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

2. Department of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

3. Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA

4. Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

5. Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

6. Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

7. Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, USA

Abstract

Members of the Mycobacterium avium complex (MAC), a group of mycobacteria encompassing M. avium and its closest relatives, are omnipresent in natural environments and emerging pathogens of humans and animals. MAC infections are difficult to treat, sometimes fatal, and increasingly common.

Funder

Cystic Fibrosis Foundation

HHS | Centers for Disease Control and Prevention

HHS | National Institutes of Health

National Science Foundation

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSystems.01194-21

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