Phylogenomic Diversity Elucidates Mechanistic Insights into Lyme Borreliae-Host Association-Reference-Cited by-同舟云学术

Phylogenomic Diversity Elucidates Mechanistic Insights into Lyme Borreliae-Host Association

Published:2022-08-30 Issue:4 Volume:7 Page:
ISSN:2379-5077
Container-title:mSystems
language:en
Short-container-title:mSystems

Author:

Combs Matthew¹²³,Marcinkiewicz Ashley L.⁴,Dupuis Alan P.⁴,Davis April D.⁴,Lederman Patricia⁴,Nowak Tristan A.⁴⁵,Stout Jessica L.⁴,Strle Klemen⁴⁵,Fingerle Volker⁶,Margos Gabriele⁶,Ciota Alexander T.⁴⁵,Diuk-Wasser Maria A.¹,Kolokotronis Sergios-Orestis²³⁷⁸^ORCID,Lin Yi-Pin⁴⁵^ORCID

Affiliation:

1. Department of Ecology, Evolution, and Environmental Biology, Columbia University, New York, New York, USA

2. Department of Epidemiology and Biostatistics, School of Public Health, SUNY Downstate Health Sciences University, Brooklyn, New York, USA

3. Institute for Genomics in Health, SUNY Downstate Health Sciences University, Brooklyn, New York, USA

4. Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York, USA

5. Department of Biomedical Sciences, SUNY Albany, Albany, New York, USA

6. German National Reference Centre for Borrelia, Bavarian Health and Food Safety Authority, Oberschleissheim, Germany

7. Division of Infectious Diseases, Department of Medicine, College of Medicine, SUNY Downstate Health Sciences University, Brooklyn, New York, USA

8. Department of Cell Biology, College of Medicine, SUNY Downstate Health Sciences University, Brooklyn, New York, USA

Abstract

Host association is the phenotype that is commonly found in many pathogens that preferential survive in particular hosts. The Lyme disease (LD)-causing agent, B. burgdorferi ( Bb ), is an ideal model to study host association, as Bb is mainly maintained in nature through rodent and avian hosts.

Funder

National Science Foundation

Publisher

American Society for Microbiology

Subject

Computer Science Applications,Genetics,Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Biochemistry,Physiology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msystems.00488-22

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4. Outer surface protein polymorphisms linked to host‐spirochete association in Lyme borreliae

5. ospC Diversity in Borrelia burgdorferi

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