Rapid Increase of CTX-M-Producing Shigella sonnei Isolates in Switzerland Due to Spread of Common Plasmids and International Clones-Reference-Cited by-同舟云学术

Rapid Increase of CTX-M-Producing Shigella sonnei Isolates in Switzerland Due to Spread of Common Plasmids and International Clones

Published:2020-09-21 Issue:10 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Campos-Madueno Edgar I.¹,Bernasconi Odette J.¹,Moser Aline I.¹,Keller Peter M.¹,Luzzaro Francesco²,Maffioli Carola³,Bodmer Thomas⁴,Kronenberg Andreas¹⁵,Endimiani Andrea¹^ORCID

Affiliation:

1. Institute for Infectious Diseases, University of Bern, Bern, Switzerland

2. Clinical Microbiology and Virology Unit, A. Manzoni Hospital, Lecco, Italy

3. MCL Medizinische Laboratorien, Niederwangen, Switzerland

4. labormedizinisches zentrum Dr. Risch, Bern-Liebefeld, Switzerland

5. Swiss Centre for Antibiotic Resistance (ANRESIS), Bern, Switzerland

Abstract

The Swiss Centre for Antibiotic Resistance (ANRESIS) has recently noted an increase of extended-spectrum cephalosporin-resistant (ESC-R) Shigella sonnei isolates nationwide (3.8% in 2016 versus 37.5% in 2019). To understand this phenomenon, we analyzed 25 representative isolates (of which 14 were ESC-R) collected in Switzerland during 2016 to 2019. Whole-genome sequencing was achieved using both the Illumina and the Nanopore platforms. Both ESC-R and extended-spectrum cephalosporin-susceptible isolates belonged to sequence type 152 (ST152).

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01057-20

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