Persistent Transmission of Shigellosis in England Is Associated with a Recently Emerged Multidrug-Resistant Strain of Shigella sonnei-Reference-Cited by-同舟云学术

Persistent Transmission of Shigellosis in England Is Associated with a Recently Emerged Multidrug-Resistant Strain of Shigella sonnei

Published:2020-03-25 Issue:4 Volume:58 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Bardsley Megan¹,Jenkins Claire¹,Mitchell Holly D.²,Mikhail Amy F. W.¹^ORCID,Baker Kate S.³,Foster Kirsty¹,Hughes Gwenda¹,Dallman Timothy J.¹

Affiliation:

1. National Infection Service, Public Health England, London, United Kingdom

2. Institute for Global Health, University College London, London, United Kingdom

3. Institute for Integrative Biology, University of Liverpool, Liverpool, United Kingdom

Abstract

Whole-genome sequencing has enhanced surveillance and facilitated detailed monitoring of the transmission of Shigella species in England. We undertook an epidemiological and phylogenetic analysis of isolates from all cases of shigellosis referred to Public Health England between 2015 and 2018 to explore recent strain characteristics and the transmission dynamics of Shigella species. Of the 4,950 confirmed cases of shigellosis identified during this period, the highest proportion of isolates was Shigella sonnei (54.

Funder

National Institute for Health Research

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01692-19

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