Genome sequences of 36 <i>Streptococcus pneumoniae</i> strains optimized for the multiplexed opsonophagocytosis killing assay-Reference-Cited by-同舟云学术

Genome sequences of 36 Streptococcus pneumoniae strains optimized for the multiplexed opsonophagocytosis killing assay

Published:2024-09-10 Issue:9 Volume:13 Page:
ISSN:2576-098X
Container-title:Microbiology Resource Announcements
language:en
Short-container-title:Microbiol Resour Announc

Author:

Graffice Emma¹^ORCID,Meewes Chloe¹,Ganaie Feroze A.²,Nahm Moon H.²,Calix Juan J.¹^ORCID

Affiliation:

1. 1Department of Medicine, Division of Infectious Disease, University of Alabama at Birmingham, Birmingham, Alabama, USA

2. Division of Pulmonary/Allergy/Critical Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA

Abstract

ABSTRACT A multiplexed opsonophagocytosis assay (MOPA) was developed as a cost-effective, high-throughput biological assay to evaluate the efficacy of pneumococcal vaccines by in vitro measurement of opsonophagocytic activity of anti-capsular antibodies. Here, we report draft genomes of the 36 strains of Streptococcus pneumoniae developed for use in the reference pneumococcal MOPA.

Publisher

American Society for Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mra.00553-24

Reference29 articles.

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2. Development and Validation of a Fourfold Multiplexed Opsonization Assay (MOPA4) for Pneumococcal Antibodies

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4. Development of a multi-specificity opsonophagocytic killing assay

5. The 15-valent pneumococcal conjugate vaccine V114 induces cross-reactive antibodies against pneumococcal serotype 6C