The 15-valent pneumococcal conjugate vaccine V114 induces cross-reactive antibodies against pneumococcal serotype 6C

Author:

Shi Yaru1,Nolan Katrina M.1,Burton Robert L.2,Shekar Tulin1,Murphy Rocio D.1,Banniettis Natalie1,Musey Luwy1,Buchwald Ulrike K.1

Affiliation:

1. Merck & Co., Inc., Rahway, NJ, USA

2. SunFire Biotechnologies LLC, Birmingham, AL, USA

Funder

Merck Sharp & Dohme LLC

Publisher

Informa UK Limited

Subject

Pharmacology,Immunology,Immunology and Allergy

Reference32 articles.

1. The 13-valent pneumococcal conjugate vaccine (PCV13) elicits cross-functional opsonophagocytic killing responses in humans to Streptococcus pneumoniae serotypes 6C and 7A

2. Comparative Immunogenicity of 7 and 13-Valent Pneumococcal Conjugate Vaccines and the Development of Functional Antibodies to Cross-Reactive Serotypes

3. The Pink Book: epidemiology and prevention of vaccine-preventable diseases. 14th ed. Chapter 17: pneumococcal disease [Internet]. Centers for Disease Control and Prevention; 2021 [accessed 2023 June 12]. https://www.cdc.gov/vaccines/pubs/pinkbook/pneumo.html.

4. Pneumococcal disease [Internet]. World Health Organization; 2021 [accessed 2021 Nov 29]. https://www.who.int/teams/health-product-policy-and-standards/standards-and-specifications/vaccine-standardization/pneumococcal-disease.

5. Current epidemiology of pneumococcal disease and pneumococcal vaccine coverage among children U.S. [Internet]. Gierke R; 2022 [accessed 2022 Sept 8]. https://www.cdc.gov/vaccines/acip/meetings/downloads/slides-2022-02-23-24/02-pneumococcal-gierke-508.pdf.

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