CADM1 and CADM2 Trigger Neuropathogenic Measles Virus-Mediated Membrane Fusion by Acting in cis

Author:

Shirogane Yuta1ORCID,Takemoto Ryuichi1,Suzuki Tateki1,Kameda Tomonori2,Nakashima Kinichi2,Hashiguchi Takao1ORCID,Yanagi Yusuke1ORCID

Affiliation:

1. Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka, Japan

2. Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Abstract

Measles virus (MeV), an enveloped RNA virus, is the causative agent of measles, which is still an important cause of childhood morbidity and mortality worldwide. Persistent MeV infection in the brain causes a fatal progressive neurological disorder, subacute sclerosing panencephalitis (SSPE), several years after acute infection.

Funder

Japan Agency for Medical Research and Development

Kyushu University

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference56 articles.

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5. Lamb RA, Parks GD. 2013. Paramyxoviridae, p 957–995. In Knipe DM, Howley PM, Cohen JI, Griffin DE, Lamb RA, Martin MA, Racaniello VR, Roizman B (ed), Fields virology, 6th ed. Lippincott Williams & Wilkins, Philadelphia, PA.

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