Discovery of a Novel (+)-γ-Lactamase from Bradyrhizobium japonicum USDA 6 by Rational Genome Mining-Reference-Cited by-同舟云学术

Discovery of a Novel (+)-γ-Lactamase from Bradyrhizobium japonicum USDA 6 by Rational Genome Mining

Published:2012-08-10 Issue:20 Volume:78 Page:7492-7495
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl. Environ. Microbiol.

Author:

Zhu Shaozhou,Gong Cuiyu,Song Dawei,Gao Shuaihua,Zheng Guojun

Abstract

ABSTRACTA novel (+)-γ-lactamase used for the resolution of racemic γ-lactam fromBradyrhizobium japonicumUSDA 6 was found as a result of sequence-structure guided genome mining. It consists of 409 amino acids, only 49% of which are identical to the amino acid sequences of the known (+)-γ-lactamase fromSulfolobus solfataricus. This is only the third (+)-γ-lactamase gene to be reported.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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