Affiliation:
1. Department of Pathology, Division of Medical Microbiology, Johns Hopkins Hospital, Baltimore, Maryland, USA
Abstract
ABSTRACT
The non-glucose-fermenting Gram-negative bacilli
Pseudomonas aeruginosa
and
Acinetobacter baumannii
are increasingly acquiring carbapenem resistance. Given their intrinsic antibiotic resistance, this can cause extremely difficult-to-treat infections. Additionally, resistance gene transfer can occur between Gram-negative species, regardless of their ability to ferment glucose. Thus, the acquisition of carbapenemase genes by these organisms increases the risk of carbapenemase spread in general. Ultimately, infection control practitioners and clinical microbiologists need to work together to determine the risk carried by carbapenem-resistant non-glucose-fermenting Gram-negative bacilli (CR-NF) in their institution and what methods should be considered for surveillance and detection of CR-NF.
Publisher
American Society for Microbiology
Cited by
88 articles.
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