Peptide Immunization as an Adjuvant to Chemotherapy in Mice Challenged Intratracheally with Virulent Yeast Cells of Paracoccidioides brasiliensis-Reference-Cited by-同舟云学术

Peptide Immunization as an Adjuvant to Chemotherapy in Mice Challenged Intratracheally with Virulent Yeast Cells of Paracoccidioides brasiliensis

Published:2006-08 Issue:8 Volume:50 Page:2814-2819
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Marques A. F.¹,da Silva M. B.¹,Juliano M. A. P.²,Travassos L. R.³,Taborda C. P.¹

Affiliation:

1. Institute of Biomedical Sciences, Department of Microbiology, University of São Paulo, São Paulo, SP, Brazil; and Departments of

2. Biophysics

3. Microbiology, Immunology and Parasitology, Federal University of São Paulo, São Paulo, SP, Brazil

Abstract

ABSTRACT Immunization with peptide P10, derived from gp43, and chemotherapy were used together in an attempt to improve treatment of paracoccidioidomycosis and prevent relapses. The combined treatment showed an additive protective effect when administered at 48 h or 30 days after intratracheal challenge. Its use is recommended to improve regular chemotherapy and reduce the duration of treatment.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00220-06

Reference11 articles.

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