Bovicin HC5, a Lantibiotic Produced by Streptococcus bovis HC5, Catalyzes the Efflux of Intracellular Potassium but Not ATP

Author:

Mantovani Hilário C.1,Russell James B.2

Affiliation:

1. Department of Microbiology, Cornell University

2. Agricultural Research Service, USDA, Ithaca, New York 14853

Abstract

ABSTRACT Bovicin HC5, a broad-spectrum lantibiotic produced by Streptococcus bovis HC5, catalyzed the efflux of intracellular potassium from Streptococcus bovis JB1, a sensitive strain. The level of ATP also decreased, but this decline appeared to be caused by the activity of the F 1 F 0 ATPase rather than efflux per se.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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