Effect of food on absorption of lomefloxacin

Author:

Hooper W D1,Dickinson R G1,Eadie M J1

Affiliation:

1. Department of Medicine, University of Queensland, Royal Brisbane Hospital, Herston, Australia.

Abstract

Twelve subjects participated in an open-label, single-dose, balanced three-way crossover study in which the absorptions of lomefloxacin were compared following (i) an overnight fast, (ii) a carbohydrate meal, and (iii) a high-fat meal. The time to peak concentration of lomefloxacin was delayed, but peak concentration in plasma and amount of drug absorbed were unchanged following both meals.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference5 articles.

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