Effect of food on enoxacin absorption-Reference-Cited by-同舟云学术

Effect of food on enoxacin absorption

Published:1987-04 Issue:4 Volume:31 Page:638-639
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Somogyi A A,Bochner F,Keal J A,Rolan P E,Smith M

Abstract

Fifteen subjects received a single 400-mg oral dose of enoxacin in the fasting state and after carbohydrate and high-fat meals. The carbohydrate meal delayed the time to peak enoxacin concentration in plasma by an average of 0.92 h. The extent of enoxacin absorption was not altered by food.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.31.4.638

Reference8 articles.

1. Daniel W. W. 1983. Biostatistics: a foundation for analysis in the health sciences p. 206-264. John Wiley & Sons Inc. New York.

2. Fluorinated quinolones: a review of their mode of action, antimicrobial activity, pharmacokinetics and clinical efficacy;Janknegt R.;Pharm. Weekbl.,1986

3. Ofloxacin: serum and skin blister fluid pharmacokinetics in the fasting and non-fasting state;Kalager T.;J. Antimicrob. Chemother.,1986

4. Effect of standard breakfast on drug absorption and multiple-dose pharmacokinetics of ciprofloxacin;Ledergerber B.;Antimicrob. Agents Chemother.,1985

5. Determination of a new antibacterial agent (AT-2266) and its metabolites in plasma and urine by high-performance liquid chromatography;Nakamura R.;J. Chromatogr. Biomed. Appl.,1983

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Together or Apart? Revealing the Impact of Dietary Interventions on Bioavailability of Quinolones: A Systematic Review with Meta-analyses;Clinical Pharmacokinetics;2024-05-28

2. Influence of oral co-administration of a preparation containing calcium and magnesium and food on enrofloxacin pharmacokinetics;Research in Veterinary Science;2014-08

3. A quantitative approach to probe the dependence and correlation of food-effect with aqueous solubility, dose/solubility ratio, and partition coefficient (LogP) for orally active drugs administered as immediate-release formulations;Drug Development Research;2005

4. Oral Bioavailability of Gatifloxacin in Healthy Volunteers under Fasting and Fed Conditions;Chemotherapy;2002

5. Effect of Food on the Pharmacokinetics of a Single Oral Dose of Moxifloxacin 400mg in Healthy Male Volunteers;Clinical Pharmacokinetics;2001