Prospective Survey of β-Lactamases Produced by Ceftazidime- Resistant Pseudomonas aeruginosa Isolated in a French Hospital in 2000-Reference-Cited by-同舟云学术

Prospective Survey of β-Lactamases Produced by Ceftazidime- Resistant Pseudomonas aeruginosa Isolated in a French Hospital in 2000

Published:2002-09 Issue:9 Volume:46 Page:3031-3034
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

De Champs Christophe¹,Poirel Laurent²,Bonnet Richard¹,Sirot Danielle¹,Chanal Catherine¹,Sirot Jacques¹,Nordmann Patrice²

Affiliation:

1. Service de Bactériologie, Faculté de Médecine, Université d'Auvergne, 63001 Clermont-Ferrand

2. Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre, France

Abstract

ABSTRACT In 2000, at the Université d'Auvergne teaching hospital in Clermont-Ferrand, France, 44 (6.2%) strains of Pseudomonas aeruginosa were found to be resistant to ceftazidime. After genotyping, 34 strains were selected. Nine had an additional β-lactamase: OXA-21 ( n = 6), PSE-1 (CARB-2) ( n = 2), or PER-1 ( n = 1). Ceftazidime resistance was related solely to the overproduction of the cephalosporinase in 30 strains. Sequencing of five bla AmpC genes encoding cephalosporinases with different pIs showed 99% identity with the ampC gene of P. aeruginosa PAO1.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.46.9.3031-3034.2002

Reference33 articles.

1. Arlet, G., and A. Philippon. 1991. Construction by polymerase chain reaction and intragenic DNA probes for three main types of transferable β-lactamases (TEM, SHV, CARB). FEMS Microbiol. Lett.82:19-26.

2. Cavallo, J. D., R. Fabre, F. Leblanc, M. H. Nicolas-Chanoine, A. Thabaut, and the GERPB. 2000. Antibiotic susceptibility and mechanisms of β-lactam resistance in 1310 strains of Pseudomonas aeruginosa: a French multicentre study (1996). J. Antimicrob. Chemother.46:133-136.

3. OXA-14, another extended-spectrum variant of OXA-10 (PSE-2) beta-lactamase from Pseudomonas aeruginosa

4. OXA-15, an extended-spectrum variant of OXA-2 beta-lactamase, isolated from a Pseudomonas aeruginosa strain

5. OXA-16, a Further Extended-Spectrum Variant of OXA-10 β-Lactamase, from Two Pseudomonas aeruginosa Isolates

Cited by 79 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enterobacter cloacae Complex and CTX-M Extended-Spectrum β-Lactamases in Algeria;Microbial Drug Resistance;2021-12-10

2. Detection of Extended-Spectrum ß-Lactamases among Acinetobacter Baumannii Isolated from Hospitals of Qazvin, Iran;Ethiopian Journal of Health Sciences;2021-03-01

3. Occurrence and distribution of antimicrobial resistance genes in the soil of an industrial park in China: A metagenomics survey;Environmental Pollution;2021-03

4. A synthetic peptide sensitizes multi-drug resistant Pseudomonas aeruginosa to antibiotics for more than two hours and permeabilizes its envelope for twenty hours;Journal of Biomedical Science;2020-08-06

5. Prevalence of Resistance to β-Lactam Antibiotics and bla Genes Among Commensal Haemophilus parainfluenzae Isolates from Respiratory Microbiota in Poland;Microorganisms;2019-10-09