Relationship between Phenotypic and Genotypic Florfenicol Resistance in Escherichia coli

Author:

Singer Randall S.12,Patterson Sheila K.1,Meier Anne E.1,Gibson Jessica K.1,Lee Hannah L.1,Maddox Carol W.13

Affiliation:

1. Department of Veterinary Pathobiology

2. Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota

3. Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Illinois, Urbana, Illinois

Abstract

ABSTRACT This study evaluated the relationship between florfenicol resistance and flo genotypes in 1,987 Escherichia coli isolates from cattle. The flo gene was detected in 164 isolates, all of which expressed resistance to florfenicol at MICs of ≥256 μg/ml. The florfenicol MICs for all isolates that lacked flo were ≤16 μg/ml.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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