bla VIM-7 , an Evolutionarily Distinct Metallo-β-Lactamase Gene in a Pseudomonas aeruginosa Isolate from the United States

Author:

Toleman Mark A.1,Rolston Kenneth2,Jones Ronald N.34,Walsh Timothy R.1

Affiliation:

1. Department of Pathology and Microbiology, University of Bristol, Bristol BS8 1TD, United Kingdom

2. Anderson Medical Center, Houston, Texas

3. The JONES Group/JMI Laboratories, North Liberty, Iowa

4. Tufts University School of Medicine, Boston, Massachusetts

Abstract

ABSTRACT As part of the CANCER Antimicrobial Surveillance Program in North America, a Pseudomonas aeruginosa isolate, strain 07-406, was shown to possess a metallo-β-lactamase, designated VIM-7. bla VIM-7 is located on a 24-kb plasmid which can be readily transferred into Enterobacteriaceae and other pseudomonads. This is the first report of a mobile metallo-β-lactamase gene, bla VIM-7 , being detected within the United States.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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