Colistin-Resistant mcr-1 -Positive Escherichia coli on Public Beaches, an Infectious Threat Emerging in Recreational Waters

Author:

Fernandes Miriam R.1,Sellera Fábio P.2,Esposito Fernanda1,Sabino Caetano P.1,Cerdeira Louise1,Lincopan Nilton13ORCID

Affiliation:

1. Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil

2. Department of Internal Medicine, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil

3. Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

Abstract

ABSTRACT The emergence and rapid spread of colistin-resistant Escherichia coli carrying the mcr-1 gene have generated an urgent need to strengthen surveillance. We performed a meticulous investigation of strains of this sort, which resulted in the identification of international clones of E. coli carrying IncX4-plasmid-mediated mcr-1 and bla CTX-M genes in recreational waters of public urban beaches in cities with high tourist turnover, highlighting a new environmental reservoir.

Funder

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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