Bioenergetic State of Escherichia coli Controls Aminoglycoside Susceptibility-Reference-Cited by-同舟云学术

Bioenergetic State of Escherichia coli Controls Aminoglycoside Susceptibility

Published:2023-02-28 Issue:1 Volume:14 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

El Khoury Jessica Y.¹²³,Zamarreño Beas Jordi⁴⁵⁶⁷,Huguenot Allison⁴⁵⁶⁷,Py Béatrice⁴⁵⁶⁷,Barras Frédéric¹²³^ORCID

Affiliation:

1. Département de Microbiologie, SAMe Unit, Institut Pasteur, Paris, France

2. Université Paris-Cité, Paris, France

3. UMR CNRS 6047, Paris, France

4. Laboratoire de Chimie Bactérienne UMR7283, Centre National de la Recherche, Marseille, France

5. Aix-Marseille Université, Marseille, France

6. Institut de Microbiologie de la Méditerranée, Marseille, France

7. Institut Microbiologie Bioénergies et Biotechnologie, Marseille, France

Abstract

Antibiotic resistance is a major public health, social, and economic problem. Aminoglycosides (AG) are known to be highly effective against Gram-negative bacteria, but their use is limited to life-threatening infections because of their nephrotoxicity and ototoxicity at therapeutic dose.

Funder

Agence Nationale de la Recherche

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03302-22

Reference39 articles.

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4. Failure of aminoglycoside antibiotics to kill anaerobic, low-pH, and resistant cultures

5. Definitions and guidelines for research on antibiotic persistence

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