Interactions of Both Pathogenic and Nonpathogenic CUG Clade Candida Species with Macrophages Share a Conserved Transcriptional Landscape

Author:

Pountain Andrew W.1ORCID,Collette John R.12,Farrell William M.1,Lorenz Michael C.1ORCID

Affiliation:

1. Department of Microbiology & Molecular Genetics, University of Texas Health Science Center at Houston, Houston, Texas, USA

2. Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA

Abstract

Candidiasis is a major fungal infection by Candida species, causing life-threatening invasive disease in immunocompromised patients. C. albicans , which is adapted to commensalism of human mucosae, is the most common cause. While several other species cause infection, most are less prevalent or less virulent.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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