Cooperation between Different CRISPR-Cas Types Enables Adaptation in an RNA-Targeting System-Reference-Cited by-同舟云学术

Cooperation between Different CRISPR-Cas Types Enables Adaptation in an RNA-Targeting System

Published:2021-04-27 Issue:2 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Hoikkala Ville¹^ORCID,Ravantti Janne²^ORCID,Díez-Villaseñor César¹,Tiirola Marja¹,Conrad Rachel A.³,McBride Mark J.³^ORCID,Moineau Sylvain⁴^ORCID,Sundberg Lotta-Riina¹^ORCID

Affiliation:

1. University of Jyväskylä Department of Biological and Environmental Science, Nanoscience Center, Jyväskylä, Finland

2. University of Helsinki, Molecular and Integrative Biosciences Research Programme, Helsinki, Finland

3. University of Wisconsin—Milwaukee, Department of Biological Sciences, Milwaukee, Wisconsin, USA

4. Université Laval, Département de Biochimie, de Microbiologie, et de Bio-informatique, Québec City, Québec, Canada

Abstract

CRISPR-Cas systems are immune systems that protect bacteria and archaea against their viruses, bacteriophages. Immunity is achieved through the acquisition of short DNA fragments from the viral invader’s genome.

Funder

Koneen Säätiö

Jane ja Aatos Erkon Säätiö

BONUS Flavophage Project

U.S. Department of Agriculture

Academy of Finland

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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