Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony-Reference-Cited by-同舟云学术

Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony

Published:2021-04-27 Issue:2 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Perrin Abigail J.¹^ORCID,Bisson Claudine²³,Faull Peter A.⁴,Renshaw Matthew J.⁵,Lees Rebecca A.²,Fleck Roland A.³,Saibil Helen R.²,Snijders Ambrosius P.⁴,Baker David A.⁶^ORCID,Blackman Michael J.¹⁶^ORCID

Affiliation:

1. Malaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom

2. Department of Biological Sciences, Institute of Structural & Molecular Biology, Birkbeck College, University of London, London, United Kingdom

3. Centre for Ultrastructural Imaging, Guy’s Campus, King’s College London, London, United Kingdom

4. Mass Spectrometry Proteomics Platform, The Francis Crick Institute, London, United Kingdom

5. Advanced Light Microscopy, The Francis Crick Institute, London, United Kingdom

6. Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom

Abstract

Malaria is a deadly infectious disease. Rationally designed novel therapeutics will be essential for its control and eradication.

Funder

Wellcome

UKRI | Medical Research Council

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.03377-20

Reference37 articles.

1. Immune Signature Against Plasmodium falciparum Antigens Predicts Clinical Immunity in Distinct Malaria Endemic Communities

2. Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis

3. Breadth and Magnitude of Antibody Responses to Multiple Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Clinical Malaria

4. Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection

5. Maternally-derived Antibodies to Schizont Egress Antigen-1 and Protection of Infants From Severe Malaria

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