Affiliation:
1. Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA
Abstract
Anthrax disease, caused by
B. anthracis
, can cause lethal bacteremia and toxemia, even following treatment with antibiotics. This report identifies the
ilvD
gene, which encodes a dihydroxyacid dehydratase, as necessary for
B. anthracis
to synthesize the amino acid isoleucine in a nutrient-limiting environment, such as its mammalian host.
Funder
HHS | NIH | National Institute of Allergy and Infectious Diseases
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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5. Anthrax
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