Pleiotropic Roles of Cholesteryl Sulfate during Entamoeba Encystation: Involvement in Cell Rounding and Development of Membrane Impermeability

Author:

Mi-ichi Fumika12ORCID,Tsugawa Hiroshi345,Arita Makoto456,Yoshida Hiroki1

Affiliation:

1. Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan

2. Central Laboratory, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan

3. Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Koganei, Tokyo, Japan

4. Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan

5. Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan

6. Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan

Abstract

Entamoeba histolytica causes a parasitic infectious disease, amoebiasis. Amoebiasis is a global public health problem with a high occurrence of infection and inadequate clinical options.

Funder

Ministry of Education, Culture, Sports, Science and Technology

AMED-J-PRIDE

AMED

Mochida Memorial Foundation for Medical and Pharmaceutical Research

MEXT | Japan Science and Technology Agency

National Cancer center research and development fund

MEXT | JST | Exploratory Research for Advanced Technology

Uehara Memorial Foundation

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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