Observational Cohort Study of Oral Mycobiome and Interkingdom Interactions over the Course of Induction Therapy for Leukemia-Reference-Cited by-同舟云学术

Observational Cohort Study of Oral Mycobiome and Interkingdom Interactions over the Course of Induction Therapy for Leukemia

Published:2020-04-29 Issue:2 Volume:5 Page:
ISSN:2379-5042
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Author:

Robinson Sarah¹,Peterson Christine B.²,Sahasrabhojane Pranoti³,Ajami Nadim J.⁴,Shelburne Samuel A.³⁴,Kontoyiannis Dimitrios P.³^ORCID,Galloway-Peña Jessica R.³^ORCID

Affiliation:

1. Department of Statistics, Rice University, Houston, Texas, USA

2. Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

3. Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

4. Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Abstract

This report highlights the importance of longitudinal, parallel characterization of oral fungi and bacteria in order to better elucidate the dynamic changes in microbial community structure and interkingdom functional interactions during the injury of chemotherapy and antibiotic exposure as well as the clinical consequences of these interrelated alterations.

Funder

Odyssey Fellowship

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

National Science Foundation

UT | University of Texas MD Anderson Cancer Center

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00048-20