Impact of Reinfection with SARS-CoV-2 Omicron Variants in Previously Infected Hamsters

Author:

Shiwa-Sudo Nozomi1,Sakai Yusuke1,Iwata-Yoshikawa Naoko1,Watanabe Shinji2,Yamada Souichi3,Kuroda Yudai4,Yamamoto Tsukasa4,Shirakura Masayuki2,Fujisaki Seiichiro2,Miyazaki Kaya2,Miura Hideka2,Nagata Shiho2,Fukushi Shuetsu3,Maeda Ken4,Hasegawa Hideki2,Suzuki Tadaki1,Nagata Noriyo1ORCID

Affiliation:

1. Department of Pathology, National Institute of Infectious Diseases, Tokyo, Japan

2. Research Center for Influenza and Respiratory Viruses, National Institute of Infectious Diseases, Tokyo, Japan

3. Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan

4. Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan

Abstract

The emergence of SARS-CoV-2 variants and the widespread use of COVID-19 vaccines has resulted in individual differences in immune status against SARS-CoV-2. A decay in immunity over time and the emergence of variants that partially evade the immune response can also lead to reinfection.

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference63 articles.

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2. World Health Organization. 2021. Classification of Omicron (B.1.1.529): SARS-CoV-2 variant of concern. https://www.who.int/news/item/26-11-2021-classification-of-omicron-(b.1.1.529)-sars-cov-2-variant-of-concern. Accessed 29 May 2022.

3. Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

4. Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

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