Affiliation:
1. Institute of Cell and Molecular Biology, University of Edinburgh, Edinburgh EH9 3JR, Scotland
Abstract
ABSTRACT
Deletion of
ftsK
results in the inhibition of cell division, but this inhibition can be reversed by a plasmid carrying only the first ∼17% of
ftsK
. The division block can be suppressed in most mutants by deletion of
dacA
, which codes for the
d
-alanine:
d
-alanine carboxypeptidase PBP5, or in all mutants by overexpression of
ftsN
. Overexpression of
ftsK
inhibits cell division and the formation of FtsZ rings. This division block is not due to the induction of either the SOS or the heat shock regulons.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Cited by
128 articles.
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