Emergence of the cfr Gene in Vibrio diabolicus of Seafood Origin-Reference-Cited by-同舟云学术

Emergence of the cfr Gene in Vibrio diabolicus of Seafood Origin

Published:2022-01-18 Issue:1 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Liu Ming¹,Zhang Wenhui²,Hu Yifan¹,Chen Pengyu¹,Wang Zhiqiang²³,Li Ruichao²³^ORCID

Affiliation:

1. Department of Marine Biology, College of Oceanography, Hohai University, Nanjing, P. R. China

2. Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University, Yangzhou, P. R. China

3. Institute of Comparative Medicine, Yangzhou University, Yangzhou, P. R. China

Abstract

The emergence and transmission of multidrug resistance (MDR) gene cfr have incurred great public health concerns worldwide. Recently, Gram-negative pathogens were found to carry cfr by various mobile elements. Here, we investigated a cfr -positive Vibrio diabolicus isolate by phenotyping and genomic analysis and found cfr in a translocatable structure (IS 26 - hp - cfr -IS 26 ) among the MDR region in pNV27-cfr-208K, an emerging MDR plasmid in Vibrio species.

Funder

MOE | Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01819-21

Reference21 articles.

1. The Cfr rRNA Methyltransferase Confers Resistance to Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A Antibiotics

2. Mobile Oxazolidinone Resistance Genes in Gram-Positive and Gram-Negative Bacteria