Complete Genome Sequence of Herpes Simplex Virus 1 Strain MacIntyre

Author:

Jiao Xiaoli1,Sui Hongyan1ORCID,Lyons Christopher2,Tran Bao2,Sherman Brad T.1,Imamichi Tomozumi1

Affiliation:

1. Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA

2. Sequencing Facility, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA

Abstract

Herpes simplex virus type 1 (HSV-1) strain MacIntyre has a severe defect in the anterograde spread after replication in the nucleus. To better understand and identify the genetic determinants that lead to the unique phenotypes of the MacIntyre strain, we sequenced its genome with PacBio single-molecule real-time sequencing technology and resolved the complete sequence.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

Reference23 articles.

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