Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae-Reference-Cited by-同舟云学术

Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae

Published:2019-09-26 Issue:39 Volume:8 Page:
ISSN:2576-098X
Container-title:Microbiology Resource Announcements
language:en
Short-container-title:Microbiol Resour Announc

Author:

Jiao Xiaoli¹,Sui Hongyan¹^ORCID,Lyons Christopher²,Tran Bao²,Sherman Brad T.¹,Imamichi Tomozumi¹

Affiliation:

1. Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA

2. Sequencing Facility, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA

Abstract

Herpes simplex virus 1 (HSV-1) strain McKrae is highly virulent and relatively neuroinvasive in animal models compared with other wild-type HSV-1 strains. To identify the genetic determinants that lead to the unique phenotypes of the McKrae strain, we sequenced its genome with PacBio single-molecule real-time (SMRT) technology and resolved the complete sequence.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/MRA.00993-19

Reference18 articles.

1. Herpes Simplex Viruses

2. Experimental Induction of Disciform Keratitis