Presence of Plasmid-Mediated Quinolone Resistance in Klebsiella pneumoniae Isolates Possessing bla KPC in the United States-Reference-Cited by-同舟云学术

Presence of Plasmid-Mediated Quinolone Resistance in Klebsiella pneumoniae Isolates Possessing bla KPC in the United States

Published:2008-07 Issue:7 Volume:52 Page:2680-2682
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Endimiani Andrea¹,Carias Lenore L.¹,Hujer Andrea M.¹,Bethel Christopher R.¹,Hujer Kristine M.¹,Perez Federico²,Hutton Rebecca A.¹,Fox William R.³,Hall Geraldine S.³,Jacobs Michael R.⁴,Paterson David L.⁵,Rice Louis B.¹,Jenkins Stephen G.⁶,Tenover Fred C.⁷,Bonomo Robert A.¹⁸

Affiliation:

1. Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio 44106

2. Division of Infectious Diseases and HIV Medicine, University Hospital Case Medical Center, Cleveland, Ohio 44106

3. Cleveland Clinic Foundation, Cleveland, Ohio 44195

4. Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106

5. University of Pittsburgh Medical Center, Pittsburgh, PA 15212

6. Mount Sinai Medical Center, New York, New York 10029

7. Office of Antimicrobial Resistance, Centers for Disease Control and Prevention, Atlanta, Georgia 30333

8. Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106

Abstract

ABSTRACT The presence of plasmid-mediated quinolone resistance genes [i.e., qnrA , qnrB , qnrS , aac(6 ′ )-Ib-cr , and qepA ] was evaluated among 42 bla KPC -containing Klebsiella pneumoniae isolates collected in the eastern United States. One isolate carried the bla KPC-3 and qnrB19 genes on the same conjugative plasmid, whereas another carried the bla KPC-3 and qnrA1 genes on separate plasmids.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00158-08

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