Affiliation:
1. Department of Bioengineering, Nagaoka University of Technology, Nagaoka, Niigata, Japan
2. Forestry and Forest Products Research Institute, Tsukuba, Ibaraki, Japan
Abstract
Syringate is a major degradation product in the microbial and chemical degradation of syringyl lignin. Along with other low-molecular-weight aromatic compounds, syringate is produced by chemical lignin depolymerization. Converting this mixture into value-added chemicals using bacterial metabolism (i.e., biological funneling) is a promising option for lignin valorization. To construct an efficient microbial lignin conversion system, it is necessary to identify and characterize the genes involved in the uptake and catabolism of lignin-derived aromatic compounds and to elucidate their transcriptional regulation. In this study, we found that the transcription of
desA
, encoding syringate
O
-demethylase in SYK-6, is regulated by an IclR-type transcriptional regulator, DesX. The findings of this study, combined with our previous results on
desR
(encoding a MarR transcriptional regulator that controls the transcription of
ligM
and
desB
), provide an overall picture of the transcriptional-regulatory systems for syringate and vanillate catabolism in SYK-6.
Funder
Forestry and Forest Products Research Institute
MEXT | Japan Society for the Promotion of Science
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Cited by
17 articles.
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