Precise Excision and Self-Integration of a Composite Transposon as a Model for Spontaneous Large-Scale Chromosome Inversion/Deletion of the Staphylococcus haemolyticus Clinical Strain JCSC1435-Reference-Cited by-同舟云学术

Precise Excision and Self-Integration of a Composite Transposon as a Model for Spontaneous Large-Scale Chromosome Inversion/Deletion of the Staphylococcus haemolyticus Clinical Strain JCSC1435

Published:2007-04 Issue:7 Volume:189 Page:2921-2925
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Watanabe Shinya¹,Ito Teruyo¹²,Morimoto Yuh¹,Takeuchi Fumihiko¹,Hiramatsu Keiichi¹²

Affiliation:

1. Department of Infection Control Science, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan

2. Department of Bacteriology, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan

Abstract

ABSTRACT Large-scale chromosomal inversions (455 to 535 kbp) or deletions (266 to 320 kbp) were found to accompany spontaneous loss of beta-lactam resistance during drug-free passage of the multiresistant Staphylococcus haemolyticus clinical strain JCSC1435. Identification and sequencing of the rearranged chromosomal loci revealed that ISSha 1 of S. haemolyticus is responsible for the chromosome rearrangements.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.01485-06

Reference20 articles.

1. Chan, R. K., D. Botstein, T. Watanabe, and Y. Ogata. 1972. Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium. II. Properties of a high-frequency-transducing lysate. Virology 50 : 883-898.

2. Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd

3. Antimicrobial resistance in nosocomial isolates of Staphylococcus haemolyticus

4. Gray, Y. H. 2000. It takes two transposons to tango: transposable-element-mediated chromosomal rearrangements. Trends Genet. 16 : 461-468.

5. Hiramatsu, K. 1998. Vancomycin resistance in staphylococci. Drug Resist. Updates 1 : 135-150.

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Characterisation of PVL-Positive Staphylococcus argenteus from the United Arab Emirates;Antibiotics;2024-04-27

2. Spontaneous Genomic Variation as a Survival Strategy of Nosocomial Staphylococcus haemolyticus;Microbiology Spectrum;2023-04-13

3. Molecular Epidemiology of Neonatal-Associated Staphylococcus haemolyticus Reveals Endemic Outbreak;Microbiology Spectrum;2022-12-21

4. How Do Transposable Elements Activate Expression of Transcriptionally Silent Antibiotic Resistance Genes?;International Journal of Molecular Sciences;2022-07-22

5. Spontaneous genomic variation as a survival strategy of nosocomial S. haemolyticus;2022-05-17