Spontaneous Genomic Variation as a Survival Strategy of Nosocomial Staphylococcus haemolyticus

Author:

Bouchami Ons12,Machado Miguel3,Carriço João André3,Melo-Cristino José3,de Lencastre Hermínia24,Miragaia Maria1ORCID

Affiliation:

1. Laboratory of Bacterial Evolution and Molecular Epidemiology, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal

2. Laboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa (ITQB-NOVA), Oeiras, Portugal

3. Instituto de Microbiologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal

4. Laboratory of Microbiology and Infectious Diseases, Rockefeller University, New York, USA

Abstract

The introduction of medical devices and antibiotics into clinical practice have substantially improved patient quality of life and contributed to extended life expectancy. One of its most cumbersome consequences was the emergence of medical device-associated infections caused by multidrug-resistant and opportunistic bacteria such as Staphylococcus haemolyticus .

Funder

MEC | Fundação para a Ciência e a Tecnologia

Fundo Europeu de Desenvolvimento Regional (FEDER) through COMPETE2020, Programa Operacional de Competitividade e Internacionalização

Fundo Europeu de Desenvolvimento Regional (FEDER) through COMPETE2020, Programa Operacional de Competetividade e Internacionalização

Fundos Europeus Estruturais e de Desenvolvimento (FEEI) from Programa Operacional Regional Lisboa2020

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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