Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis-Reference-Cited by-同舟云学术

Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis

Published:2001-07-15 Issue:14 Volume:183 Page:4389-4392
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Belitsky Boris R.¹,Brill Jeanette²,Bremer Erhard²,Sonenshein Abraham L.¹

Affiliation:

1. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts 02111,1 and

2. Laboratory for Microbiology, Department of Biology, Philipps University Marburg, D-35032 Marburg, Germany2

Abstract

ABSTRACT The complete Bacillus subtilis genome contains four genes ( proG, proH, proI, and comER ) with the potential to encode Δ 1 -pyrroline-5-carboxylate reductase, a proline biosynthetic enzyme. Simultaneous defects in three of these genes ( proG, proH, and proI ) were required to confer proline auxotrophy, indicating that the products of these genes are mostly interchangeable with respect to the last step in proline biosynthesis.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.183.14.4389-4392.2001

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