Analysis of Toxigenic Corynebacterium ulcerans Strains Revealing Potential for False-Negative Real-Time PCR Results-Reference-Cited by-同舟云学术

Analysis of Toxigenic Corynebacterium ulcerans Strains Revealing Potential for False-Negative Real-Time PCR Results

Published:2008-01 Issue:1 Volume:46 Page:331-333
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Cassiday Pamela K.¹,Pawloski Lucia C.¹,Tiwari Tejpratap²,Sanden Gary N.¹,Wilkins Patricia P.¹

Affiliation:

1. National Center for Infectious Diseases

2. National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia

Abstract

ABSTRACT Diphtheria surveillance depends on the rapid and reliable recognition of the toxin gene in Corynebacterium diphtheriae . Real-time PCR is a rapid tool to confirm the presence of the diphtheria toxin gene ( tox ) in an isolate or specimen. We report that some toxigenic Corynebacterium ulcerans strains show atypical results in a real-time PCR for tox .

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01251-07

Reference21 articles.

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3. Comparison of Phenotypic and Genotypic Methods for Detection of Diphtheria Toxin among Isolates of Pathogenic Corynebacteria

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