Affiliation:
1. Department of Biology, Technion–Israel Institute of Technology, Haifa, Israel
2. Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
Abstract
Bacteria often reside in multicellular communities, called biofilms, held together by an extracellular matrix. In many bacteria, the major proteinaceous component of the biofilm are amyloid fibers. Amyloids are highly stable and structured protein aggregates which were known mostly to be associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases. In recent years, microbial amyloids were identified also in other species and shown to play major roles in microbial physiology and virulence.
Funder
U.S. Israel Binational grant
Israel Science Foundation
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology,Infectious Diseases
Cited by
33 articles.
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