Deletion of the H240R Gene of African Swine Fever Virus Decreases Infectious Progeny Virus Production Due to Aberrant Virion Morphogenesis and Enhances Inflammatory Cytokine Expression in Porcine Macrophages-Reference-Cited by-同舟云学术

Deletion of the H240R Gene of African Swine Fever Virus Decreases Infectious Progeny Virus Production Due to Aberrant Virion Morphogenesis and Enhances Inflammatory Cytokine Expression in Porcine Macrophages

Published:2022-02-09 Issue:3 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Zhou Pingping¹,Li Lian-Feng¹,Zhang Kehui¹,Wang Bing¹,Tang Lijie²,Li Miao¹,Wang Tao¹,Sun Yuan¹,Li Su¹,Qiu Hua-Ji¹^ORCID

Affiliation:

1. State Key Laboratory of Veterinary Biotechnology, National African Swine Fever Para-reference Laboratory, National High Containment Facilities for Animal Diseases Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, China

2. Northeast Agricultural University, Harbin, China

Abstract

African swine fever is a lethal hemorrhagic disease of global concern that is caused by African swine fever virus (ASFV). Despite extensive research, there exist relevant gaps in knowledge of the fundamental biology of the viral life cycle.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01667-21

Reference53 articles.

1. Common Origin of Four Diverse Families of Large Eukaryotic DNA Viruses

2. Evolutionary genomics of nucleo-cytoplasmic large DNA viruses

3. African swine fever virus replication and genomics