Intra-Host Evolution Provides for the Continuous Emergence of SARS-CoV-2 Variants

Author:

Landis Justin T.12,Moorad Razia12,Pluta Linda J.12,Caro-Vegas Carolina12,McNamara Ryan P.12ORCID,Eason Anthony B.12,Bailey Aubrey3,Villamor Femi Cleola S.12,Juarez Angelica12,Wong Jason P.12,Yang Brian12,Broussard Grant S.12,Damania Blossom12ORCID,Dittmer Dirk P.12ORCID

Affiliation:

1. Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA

2. Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, USA

3. Kuopio Center for Gene and Cell Therapy, Kuopio, Finland

Abstract

New SARS-CoV-2 variants can potentially disrupt ongoing public health measures and vaccine efforts. Still, little is known regarding how frequently new viral variants emerge and under what circumstances.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Dental and Craniofacial Research

National Cancer Center

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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